SLU Researchers Begin Enrolling Adolescents in Mpox Vaccine Clinical Trial
04/06/2023
Researchers at 新澳门六合彩开奖结果鈥檚 Center for Vaccine Development are inviting volunteers between the ages of 12-17 and 18-50 to participate in a national clinical trial involving the JYNNEOS mpox, formerly known as monkeypox, vaccine. The trial will evaluate the safety and immune response after two doses of JYNNEOS are administered subcutaneously to adolescents compared to adults.
The JYNNEOS vaccine, which is the only FDA-approved vaccine for mpox, has a well-known safety profile in adults. The vaccine is currently only licensed for use in adults, and therefore the purpose of this clinical trial is to study whether the licensed dose is safe and elicits immune responses in adolescents that are comparable to those in adults.
The study is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. SLU鈥檚 participation is funded through a contract with Frederick National Laboratory for Cancer Research, operated by Leidos Biomedical Research in Frederick, Maryland, which provides scientific support to NIH.
鈥淲hile mpox isn鈥檛 as deadly as smallpox, it is a serious illness that causes painful lesions,鈥� said Sharon Frey, M.D., clinical director of the 新澳门六合彩开奖结果 Center for Vaccine Development and principal investigator of the current trial.
The SLU Vaccine Center will enroll volunteers in the Phase 2 clinical trial. Adolescent participants must be between 12-17 and not have previously received a mpox or smallpox vaccination or had mpox. Participation in the trial may last about 13 months.
鈥淲hile the initial mpox outbreak has subsided, the odds are good that cases may increase at some point in the future,鈥� Frey said. 鈥淢pox can be spread simply through close contact and also sexual activity. Young people are among those who are at risk and so it鈥檚 important that we study the mpox vaccine in this age group.鈥�
Interested participants should contact the 新澳门六合彩开奖结果 Center for Vaccine Development.
- Email: vaccine@slu.edu
- Telephone: 314-977-6333
For more information about the trial, visit . The study鈥檚 Clinical Trials Identifier is NCT05740982.
SLU Center for Vaccine Development
新澳门六合彩开奖结果 has been on the front lines in the fight against pandemics and global health crises for more than three decades and first received federal funding for vaccine research in 1989.
Led by Daniel Hoft, M.D., Ph.D., SLU鈥檚 Center for Vaccine Development is one of only 10 institutions selected by the National Institutes of Health as a Vaccine and Treatment Evaluation Unit (VTEU).
As a VTEU, the center helps develop and evaluate vaccines that will protect people from infectious diseases and emerging threats. It conducts Phase 1 through 4 vaccine and treatment trials, including clinical studies in collaboration with industry partners.